Degenerative Myelopathy
Breed: Borzoi/ Russian Hunting Sighthound
Breeds in this Condition
        
            Breeds
        
    
    
        
            Condition
        
    
    
            Degenerative Myelopathy
            
        
        
        
            Synonym
        
    
    
            DM,Degenerative Myelopathie,Myélopathie dégénérative,Degenerativ myelopati,Degeneratiivinen myelopatia,Degeneratieve Myelopathie
            
        
        
        
            Condition Description
        
    
    
            DM is an incompletely penetrant autosomal recessive disease, usually affecting dogs 5 years of age or older. The mutation tested for in most breeds is the SOD1:c.118A, referred to as SOD1-A or exon 2. In the Bernese Mountain Dog breed two direct DNA tests
            
        
        
        
            Specific Condition(s)
        
    
    
            Degenerative Myelopathy
            
        
        
        
            Test Types(s)
        
    
    
            genetic/genomic; necropsy
            
        
        
        
            Specific test/ grading system 1
        
    
    
            Can only be definitively diagnosed by post-mortem examination of the spine
            
        
        
        
            Type
        
    
    
            Disease/ disorder
            
        
        
        
            System
        
    
    
            Neurological
            
        
        
        
            Anatomic Location
        
    
    
            spine
            
        
        HSP Test-Specific Data
German Sighthound Breeding and Racing Association
        
            HSP
        
    
    
        
            HSP Name 2
        
    
    
            Deutscher Windhundzucht- und Rennverband e.V.
            
        
        
        
            Breed
        
    
    
        
            Condition
        
    
    
        
            Specific test type(s)
        
    
    
            Genetic / Genomic
            
        
        Required by HSP
    
        
            Date
        
    
    
            03/23/2023 07:00  AM
            
        
        
        
            Country
        
    
    
            Germany
            
        
        
        
            Country code
        
    
    
            DE
            
        
        Finnish Borzoi Club
        
            HSP
        
    
    
        
            HSP Name 2
        
    
    
            Suomen Borzoiklubi - The Finnish Borzoi Club ry
            
        
        
        
            Breed
        
    
    
        
            Condition
        
    
    
        
            Specific Condition[s]
        
    
    
            DM; genes: SOD1; SOD1-B
            
        
        
        
            Specific test type(s)
        
    
    
            genetic/genomic
            
        
        
        
            Required Comment
        
    
    
            -
            
        
        Recommended
    
        
            Recommended Comment
        
    
    
            -
            
        
        
        
            Recognized Comment
        
    
    
            -
            
        
        
        
            Date
        
    
    
            02/03/2023 07:37  PM
            
        
        
        
            Country
        
    
    
            Finland
            
        
        
        
            Country code
        
    
    
            FI
            
        
        
        
            Additional Information
        
    
    
Borzoi Ring (Sweden)
        
            HSP
        
    
    
        
            HSP Name 2
        
    
    
            Borzoi-Ringen
            
        
        
        
            Breed
        
    
    
        
            Condition
        
    
    
        
            Specific Condition[s]
        
    
    
            DM; genes: SOD1; SOD1-B
            
        
        
        
            Specific test type(s)
        
    
    
            genetic/genomic
            
        
        
        
            Required Comment
        
    
    
            -
            
        
        Recommended
    
        
            Recommended Comment
        
    
    
            -
            
        
        
        
            Recognized Comment
        
    
    
            -
            
        
        
        
            Date
        
    
    
            02/03/2023 07:37  PM
            
        
        
        
            Country
        
    
    
            Sweden
            
        
        
        
            Country code
        
    
    
            SE
            
        
        
        
            Additional Information
        
    
    
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