Reminder: Login to access new features and members-only content!

Register to be a member of our community. Its easy!

Register a new account

Already a member?

Log In here!

Donate

Did you find our content interesting or helpful? Help support the IPFD enhance health, well-being and welfare for dogs everywhere.

Jump to content

    This article highlights DogWellNet content and resources that can assist puppy buyers, new or existing owners, dog breeders, breed managers and veterinarians to answer basic questions that pertain to health, welfare, management and breeding of dogs. And to find link to international resources.

    Do you have a question about a breed - about a breed-specific health condition - about health screening or genetic tests? Are you looking for guidelines or example programs that can enhance practices that improve the quality of human and dog interactions?

    Through collaboration and working with our partners and breed experts we are continually compiling and collating information that may be helpful to you.  Check into DogWellNet.com often... bookmark this page for a list of resources.

     

    dogwellnetlogo.pngDogWellNet.com - so much better than a Google search or social media post: 

    • Impartial, accurate, evidence-based data, information, and commentary from IPFD consultants and global experts  collage.png
    • In collaboration with our partners - kennel and breed clubs, academics, specialists and veterinarians; international resources 
    • The Big Picture - how the complexities of health, welfare, and human-animal interactions come together.  For all dogs. 

       

    By typical questions:

     


  Report Entry


User Feedback

Recommended Comments

Has Neuronal Ceroid Lipofuscinosis been detected in the English Setter population outside of a laboratory colony since the test for NCL8 was developed in 2014?  I'm well aware of the history of the disease which was first discovered in Norway in the 1950's, but after more than 40 years of having English Setters in the USA, I've never heard of a case in my breed here.  The test for NCL8 is available from a few American labs, but I think I'm one of the few who has used it (with Normal results from a dog with an imported sire having several Norwegian ancestors). In contrast, a number of European clubs either require or recommend the NCL8 test.  What is the current status of this disease?

Jane Burrows

Link to comment
Share on other sites

The prevelance of NCL8 mutations in English Setter populations globally, is unknown. In part, this is due to there not being a centralised database collecting this information, or depending on the country, any collation of genetic or health test results. With panel testing being a common form of genetic testing, having all the possible (e.g. rare) variants included mean we might in future have a bit more information on the frequency of mutation and any impacts breeding strategies may have. As for why some countries include this test, it is typically down to input from the national breed clubs, researchers/veterinary advisors, test availability, and disease risk/severity. The breed relevance ratings IPFD uses is based on the availability of breed-specific research that indicates the variant being tested for is causal for the disease, not on it being "recommended" as that can vary depending on a number of population-specific factors. 

Link to comment
Share on other sites



Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Add a comment...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.


×
×
  • Create New...

Important Information

By using this site, you agree to our Terms of Use.